htsjdk.tribble.util.popgen

Class HardyWeinbergCalculation

java.lang.Object

htsjdk.tribble.util.popgen.HardyWeinbergCalculation

public final class HardyWeinbergCalculation
extends java.lang.Object

This class calculates a HardyWeinberg p-value given three values representing the observed frequences of homozygous and heterozygous genotypes in the test population.

Method Summary

Methods

Modifier and Type	Method and Description
static double	hwCalculate(int obsAA, int obsAB, int obsBB) Calculates exact two-sided hardy-weinberg p-value.

Methods inherited from class java.lang.Object

clone, equals, finalize, getClass, hashCode, notify, notifyAll, toString, wait, wait, wait

Method Detail

hwCalculate

public static double hwCalculate(int obsAA,
                 int obsAB,
                 int obsBB)

Calculates exact two-sided hardy-weinberg p-value. Parameters are number of genotypes, number of rare alleles observed and number of heterozygotes observed. (c) 2003 Jan Wigginton, Goncalo Abecasis (goncalo@umich.edu)